When Supernatural first aired in 2005, few could have anticipated the cultural impact and dedicated fan base it would create. Created by Eric Kripke, the show centers around two brothers, Sam and Dean Winchester, who travel across the U.S. hunting demons, ghosts, monsters, and other supernatural beings, all while grappling with personal loss, familial duty, and a destiny far greater than themselves.

At its core, Supernatural follows Sam (Jared Padalecki) and Dean Winchester (Jensen Ackles), who were raised to hunt the paranormal after the mysterious death of their mother. Their father, John Winchester, spent his life hunting the entity that killed his wife, leaving his sons to follow in his footsteps. The show’s early seasons focus on a “monster-of-the-week” format, with the brothers taking on a new supernatural entity in each episode, but as the series evolves, it delves into deeper mythological arcs that touch on heaven, hell, angels, demons, and even the apocalypse.