In “Rambo 6: New Blood,” John Rambo (Sylvester Stallone) is once again pulled out of a quiet life, now living in seclusion in a remote part of South America. Haunted by his past and struggling with the scars of previous battles, Rambo has tried to distance himself from violence. However, his peace is shattered when he learns that a brutal cartel is terrorizing local villages, trafficking people, and causing widespread devastation.

Rambo initially refuses to get involved, but when he discovers that a group of mercenaries, led by a former military operative named Frank Keller (Jon Bernthal), is covertly working to take down the cartel, he is reluctantly drawn back into the fight. Keller, a younger and equally tough soldier, has a personal vendetta against the cartel, which murdered his family. Despite their shared enemy, Keller and Rambo have different approaches and ideologies, leading to tension and mistrust between them.