“Slither” (2006) is a horror-comedy film written and directed by James Gunn, known for its blend of gruesome horror and dark humor. The film stars Nathan Fillion, Elizabeth Banks, Michael Rooker, and Gregg Henry.

The story takes place in the small town of Wheelsy, where a meteorite crashes, unleashing a parasitic alien organism. The parasite infects Grant Grant (Michael Rooker), a local resident, and begins to transform him into a grotesque creature. As Grant mutates, he starts infecting other townspeople, turning them into mindless, slug-like monsters under his control.

Sheriff Bill Pardy (Nathan Fillion), along with Grant’s wife, Starla (Elizabeth Banks), and a small group of survivors, must figure out how to stop the rapidly spreading infection before the entire town is consumed by the alien invasion.

The film escalates into a battle for survival as the group fights off hordes of monstrous creatures while trying to find a way to stop the alien parasite.

“Slither” is celebrated for its throwback to classic horror films of the 1980s, combining body horror with sharp, witty dialogue and over-the-top, gory special effects. While the movie didn’t perform well at the box office, it has since gained a cult following for its unique blend of horror and comedy, James Gunn’s signature style, and its homage to B-movie creature features.